User:AlonLevy/My case for phoenix tears english

Hebrew version

There is a procedure for creating an oil from cannabis flowers, that oil has a number of names, usually just cannabis oil, but it is separate from cannabis seeds oil, or from several other procedures to create cannabis oil. The oil I am talking about is called "Phoenix Tears", also known as Rick Simpson Oil after the inventor. The production procedure is dissolving of the cannabis flowers in isopropyl alcohol and controlled heating for evaporating same alcohol, see complete details in [1a] [2].

I claim that this cannabis oil (1) may cure cancer, (2) reduces mainstream cancer treatment side effects (chemo and radiation), and (3) will not cause harm. I will now try to support my claims.

May cure cancer:
 * 1) There are anecdotal evidence of complete remission [1], [1b]
 * 2) I've spoken with people who gave the oil to 300 patients, out of which 100 cancer patients. Out of the total 40-50 responded in objective partial remission (MRI/CT/Other relevant medical tests).
 * 3) There is research showing the selective effect of the main cannabinoids THC, CBD on tumors [3], [4], [13], [14], [15], [16]. Several books as well [5], [6]
 * 4) There is evidence suggesting the THC used by itself is not effective ([7] out of [5])

Helps with side effects and will not cause harm:
 * 1) Usage of cannabis during chemotheraphy and radiation therapy does not lead to interaction, and medical cannabis is supplied to chemotheraphy patients against pain, for nausea and to enhance the appetite [12]. The usage of medical cannabis in Israel and in the world by cancer patients for alleviation of side effects is well known.

Additionally:
 * 1) While scientific publications on the oil are missing, there is an approved drug called Sativex ([9], [10]) for multiple sclerosis side effects that contains similar concentrations [appendix A].
 * 2) Cannabis science is working on cannabis based drugs and they mention anti neoplasm (i.e. cancer) activity [8]
 * 3) Quoting Prof. Grinspoon "There is overwhelming evidence of its efficacy in treating a wide range of medical conditions and, very importantly, of its safety and lack of significant side effects" [17], quoting [18].

[1a] "Run from the cure" video, [http://www.youtube.com/watch?feature=player_embedded&v=Ijwpv6x2R6U#! part 2]: Hemp Oil Dosage Information

[1b] Michelle Aldrich cancer free

[2] "Phoenix Tears - The Rick Simpson story" - a book by Rick Simpson, little hard information, a lot of anecdotes given by Rick about patients. - http://phoenixtears.ca/buy-phoenixtears-the-rick-simpson-story/

[3] Munson, A.E., et al., "Anticancer Activity of Cannabinoids, "Journal of National Cancer Institute 55, (September 1975): 597

[4] Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells. Molecular Cancer Theraphy, Nov 2007, McAllister SD, Christian RT, Horowitz MP, Garcia A, Desprez PY. doi: 10.1158/1535-7163.MCT-07-0371

[5] Marijuana Gateway to Health: How Cannabis Protects Us from Cancer and Alzheimer's Disease / Clint Werner

[6] Chapter 7 "Cannabinoids and Cancer" of Integrative Oncology / Donald Abrams and Andrew Weil

[7] New Mexico State Department of Health, "Oral Vs. Inhaled cannabinoids for Nausea/ Vomiting from Cancer Chemotherapy" (November, 1986)

[8] https://www.cannabisscience.com/

[9] Sativex - Summary of product characteristics http://www.gwpharm.com/uploads/110728a-uk-spc.pdf או http://www.gwpharm.com/SmPC.aspx

[10] Link to Israely ministry of health giving permission to use Sativex for multiple sclerosis side effects http://www.health.gov.il/Services/Committee/vsal/HSB2013/DocLib1/sal22112012.pdf

[11] http://www.ironlabsllc.co/ iron laboratories

[12] A randomized, placebo-controlled, crossover trial of cannabis cigarettes in neuropathic pain. http://www.neurology.org/content/68/7/515.abstract

[13] Foroughi et al. 2011. Spontaneous regression of septum pellucidum/forniceal pilocytic astrocytomas -- possible role of cannabis inhalation. Child's Nervous System 27: 671-679.

[14] Cafferal et al. 2006. Delta-9-Tetrahydrocannabinol inhibits cell cycle progression in human breast cancer cells through Cdc2 regulation. Cancer Research 66: 6615-6621.

[15] Sarfaraz et al. 2005. Cannabinoid receptors as a novel target for the treatment of prostate cancer. Cancer Research 65: 1635-1641.

[16] Cannabinoids effects on cancer, a compilation of articles http://norml.org/library/item/gliomascancer

[17] Prof. Grinspoon about the need to avoid claims on curing cancer by cannabis http://www.clear-uk.org/professor-grinspoon-on-the-crazy-stoner-claims-about-cannabis-and-cancer/

[18] Review of research on medical cannabis usage between 2000 and 2012 http://norml.org/library/recent-research-on-medical-marijuana

= Appendix A =

Comparison of concentrations of THC and CBD between Sativex and Pheonix tears:

From [10]:
 * 1) A single dose of Sativex includes 27 mg of THC and 25 mg of CBD
 * 2) 12 doses per day
 * 3) Total per day: 324 mg THC, 300 mg CBD
 * 4) Sensitivity tests included up to 48 doses per day: 1296 mg THC and 1200 mg CBD.

Out of [11] and assuming 1 gr per day:
 * 1) Assuming 60% THC (numbers vary between 50-80) and 10% CBD (numbers vary between 5-70)
 * 2) Total per day: 600 mg THC and 100 mg CBD